Thermo Fisher Scientific SERPINB6B Recombinant Rabbit Monoclonal Antibody (202)

Applications

ELISA (ELISA)

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in HEK293 cells. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody specifically recognizes Mouse Serpinb6b.

Target Information

The protein encoded by this gene belongs to the serpin superfamily and the ovalbumin-serpin subfamily. It was initially identified as a placental thrombin inhibitor. The mouse homolog is expressed in the hair cells of the inner ear. Mutations in this gene are linked to nonsyndromic progressive hearing loss, indicating its role in protecting inner ear cells from lysosomal leakage during stress. Loss of this protection can lead to cell death and sensorineural hearing loss. Alternatively spliced transcript variants have also been identified.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.