Thermo Fisher Scientific BRD2 Monoclonal Antibody (1H6B12)
BRD2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 ELISA 및 Western blot에 적합. 인간 BRD2 (AA 227-364) 재조합 단백질을 면역원으로 사용. 고순도 Protein G 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6B12 |
| Immunogen | Purified recombinant fragment of human BRD2 (AA: 227–364) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787279 |
Product Specific Information
MA5-31655 has been tested in indirect ELISA.
Target Information
This gene encodes a transcriptional regulator belonging to the BET (bromodomains and extra terminal domain) family of proteins. It associates with transcription complexes and acetylated chromatin during mitosis, selectively binding to the acetylated lysine-12 residue of histone H4 via its two bromodomains.
The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests it is not involved in the immune response.
This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described, but the full-length nature of some variants remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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