Thermo Fisher Scientific Fibrillin 1 Polyclonal Antibody
Fibrillin 1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. PBS 기반 용액 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FBN1 (Accession P35555), corresponding to amino acid residues V2823–H2871 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818158 |
Product Specific Information
Antibody detects endogenous levels of total Fibrillin 1.
Target Information
Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape, composed of various extracellular modules. It contains 47 EGF-like repeats, 43 of which have a calcium-binding consensus sequence. Additional modules include 8-cysteine motifs, hybrid motifs, and unique domains. Fibrillin 1 has a proline-rich region near the N-terminus, replaced by a glycine-rich region in Fibrillin 2. Fibrillins are found throughout connective tissue as key components of fibrils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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