Thermo Fisher Scientific TRIM58 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TRIM58. Recombinant protein control fragment (Product #RP-93602). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRIM58,uniProtId:Q8NG06-1,ncbiNodeId:9606,antigenRange:418-486,antigenLength:486,antigenImageFileName:PA5-54856_TRIM58_Q8NG06-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54856_TRIM58_Q8NG06-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.20 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648934

Product Specific Information

Immunogen sequence: EAGEISFYNV TDGSYIYTFN QLFSGLLRPY FFICDATPLI LPPTTIAGSG NWASRDHLDP ASDVRDDHL

Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 71%.

Target Information

E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.