
Thermo Fisher Scientific SMCR7L Polyclonal Antibody
SMCR7L 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody입니다. Western blot에 적합하며 인간 시료에 반응합니다. 액상 형태로 제공되며, 0.5 mg/mL 농도와 PBS/sucrose buffer에 보관됩니다. 미토콘드리아 분열 관련 연구에 활용됩니다.
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Thermo Fisher Scientific SMCR7L Polyclonal Antibody
Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SMCR7L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577076 |
Product Specific Information
- Peptide sequence: GAAMLGIATL AVKRMYDRAI SAPTSPTRLS HSGKRSWEEP NWMGSPRLLN
- Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
Mitochondrial outer membrane protein regulating mitochondrial fission. Promotes recruitment and association of dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of FIS1 and MFF. Regulates DNM1L GTPase activity and oligomerization. Binds ADP and GDP (lower affinity), but not CDP, UDP, ATP, AMP, or GTP. Inhibits DNM1L GTPase activity without ADP; ADP is required for stimulating GTPase activity and forming long, spiral oligomeric tubules. Does not require ADP for DNM1L recruitment. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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