Thermo Fisher Scientific TGF alpha Polyclonal Antibody
인간, 랫드, 소의 TGF-alpha를 인식하는 Sheep polyclonal 항체. EGF 수용체 신호 경로 연구에 적합. ELISA 등 다양한 어세이에 사용 가능. 액상 형태로 제공되며 4°C 또는 -20°C 보관. 연구용 전용 제품.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mature human recombinant TGF-alpha conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.1 mg/mL |
| Storage conditions | 4°C or -20°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_2201773 |
Product Specific Information
Sheep anti-Human TGF alpha antibody recognizes TGF-alpha (transforming growth factor alpha) from human, rat, and bovine tissues and fluids.
Target Information
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independent transformation in cultured cells. Human, murine, and rat TGF-alpha are cross-species reactive. TGF-alpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing a reversible transformed phenotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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