Thermo Fisher Scientific TIMP1 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 TIMP1 단백질을 인식합니다. Western blot, IHC, ELISA 등 다양한 응용에 적합합니다. 비중화 항체로 단백질 활성에는 영향을 주지 않습니다. 연구용으로 세포 신호전달 및 단백질 억제 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 5–10 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–5 µg/mL | - |
| ELISA | 2.5–10 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human tissue inhibitor of metalloproteinase 1 (TIMP-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2256100 |
Product Specific Information
This antibody does not neutralize the protein activity.
Rabbit anti-Human TIMP-1 antibody recognizes human Tissue inhibitor of metalloproteinases 1 (TIMP-1), also known as Metalloproteinase inhibitor 1, Erythroid-potentiating activity, or Fibroblast collagenase inhibitor.
Target Information
TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that forms one-to-one complexes with target metalloproteinases such as collagenases, irreversibly inactivating them by binding to their catalytic zinc cofactor.
TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16.
It also functions as a growth factor that regulates cell differentiation, migration, and apoptosis, and activates signaling cascades via CD63 and ITGB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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