Thermo Fisher Scientific TRIB3 Monoclonal Antibody (OTI1F6), TrueMAB
인간 TRIB3 단백질에 특이적인 마우스 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. NF-kB 신호 억제 연구 및 종양 관련 단백질 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–200 of human TRIB3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TRIB3 (also known as TRB-3, SINK, SKIP3) is a member of the Tribbles family, originally identified as a mitosis inhibitor in Drosophila.
In mammals, TRIB3 regulates MAPK activity and inhibits NF-kB-dependent transcription induced by TNF without affecting NF-kB nuclear translocation or DNA binding.
TRIB3 is overexpressed in multiple human tumors and is regulated by hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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