Thermo Fisher Scientific TRIB3 Monoclonal Antibody (OTI3C6), TrueMAB
TRIB3 단백질을 인식하는 mouse monoclonal 항체로, Western blot 및 IHC(P) 응용에 적합합니다. Human에 반응하며, Lyophilized 형태로 제공됩니다. 연구용으로 NF-κB 신호 조절 및 종양 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–200 of human TRIB3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TRIB3 (also known as TRB-3, SINK, SKIP3) is a member of the Tribbles family, acting as a novel inhibitor of cell division. Mammalian homologues regulate mitogen-activated protein kinase (MAPK) activity. Overexpression of TRIB3 inhibits NF-κB-dependent transcription induced by TNF stimulation without affecting NF-κB nuclear translocation or DNA binding. TRIB3/SKIP3 is overexpressed in multiple human tumors and regulated by hypoxia.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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