Thermo Fisher Scientific MEK2 N-Term Monoclonal Antibody (19G10.F1.E2)
MEK2 단백질의 N-말단을 인식하는 Thermo Fisher Scientific의 mouse monoclonal antibody입니다. Western blot 및 ELISA에 최적화되어 있으며 Human, Mouse, Rat에서 반응합니다. 단백질 A로 정제된 액상 형태로 제공되며 -20°C에서 안정적으로 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
ELISA
- Tested Dilution: 1:40,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 19G10.F1.E2 |
| Immunogen | Synthetic peptide corresponding to amino acid residues near the N-terminus conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
- Biotin
- DyLight 680
- DyLight 800
- FITC
- HRP
- Custom conjugation available upon request
Product Specific Information
Store vial at -20°C prior to opening. Product is stable at 4°C as an undiluted liquid. For extended storage, aliquot and freeze at -20°C or below. Avoid freeze/thaw cycles. Dilute only prior to immediate use.
Cross-reactivity is expected with human, mouse, and rat based on sequence identity of the peptide immunogen. This antibody does not react with the MEK1 isoform.
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase involved in mitogen growth factor signal transduction. MEK2 activates ERK1/2 and MAPK enzymes by phosphorylating residues within the TEY motif in the activation loop. MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222. Threonine 292 of MEK1 is phosphorylated by ERK2, serving as a negative feedback mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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