Thermo Fisher Scientific TOP1MT Polyclonal Antibody
Human TOP1MT 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TOP1MT. Recombinant protein control fragment (Product # RP-100993) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648818 |
Product Specific Information
Immunogen sequence:
GYCILDGHQE KIGNFKIEPP GLFRGRGDHP KMGMLKRRIT PEDVVINCSR DSKIPEPPAG HQWKEVRSDN TVTWLAAWTE SVQNSIKYIM LNPCSKLKGE TAWQKFETAR RLRGFVDEIR SQYRADWKSR EMKTRQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 83%
Target Information
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology.
The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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