Thermo Fisher Scientific KLF4 Polyclonal Antibody
KLF4 단백질을 인식하는 Thermo Fisher Scientific의 고품질 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ELISA 등 다양한 연구용 응용에 적합. 사람 및 생쥐 반응성 보유. Affinity chromatography로 정제된 액상 항체로 안정적인 저장 및 재현성 제공.
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Thermo Fisher Scientific KLF4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to N-terminal portion of human KLF4 conjugated to Keyhole Limpet Hemocyanin (KLH) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid repeated freeze/thaw cycles.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
- This affinity purified antibody is directed against human KLF4.
- Blast analysis shows 100% identity with human and 93% identity with mouse sequences.
Target Information
Kruppel-like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. Also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF), it belongs to the Kruppel-like family of DNA-binding zinc finger transcription factors.
KLF4 is one of the four Yamanaka factors, playing a key role in reprogramming differentiated cells into pluripotent stem cells. It is involved in endothelial cell signaling, adipogenesis, differentiation, embryogenesis, and cell cycle control.
Nuclear localization is associated with oncogenic function, while cytosolic localization relates to tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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