
Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI2C12), TrueMAB
인간 DOK7 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Western blot에 1:2,000 희석 비율로 사용 가능. 무보존제, 동결건조 형태로 제공되며 PBS와 trehalose 버퍼에 저장. 신경근 시냅스 형성 연구용으로 적합.
- 카탈로그번호
- CF504787
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C12 |
| Immunogen | Full length human recombinant protein of human DOK7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The DOK7 gene encodes a protein essential for neuromuscular synaptogenesis. It functions in aneural activation of muscle-specific receptor kinase (MuSK), required for postsynaptic differentiation and acetylcholine receptor clustering in myotubes. DOK7 also induces MuSK autophosphorylation. Mutations in DOK7 cause familial limb-girdle myasthenia autosomal recessive (congenital myasthenic syndrome type 1B). Alternative splicing yields multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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