Thermo Fisher Scientific RET Proto-oncogene Monoclonal Antibody (RET/2663)
RET 단백질을 표적으로 하는 마우스 단일클론 항체로, IHC, ELISA, Peptide Array 등 다양한 응용에 적합합니다. 인간 시료에 반응하며 Protein A/G로 정제된 액상형 제품입니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Peptide Array
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RET/2663 |
| Immunogen | Recombinant fragment (around aa 702–848) of human RET protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been identified, though additional variants have been described without confirmed biological validity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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