Thermo Fisher Scientific RET Proto-oncogene Monoclonal Antibody (RET, 2976)
RET 단백질을 인식하는 mouse monoclonal antibody로, 인간 시료에 반응합니다. ELISA 및 Peptide Array에 사용 가능하며, 단백질 A/G로 정제된 액상형 항체입니다. PBS(pH 7.4) 버퍼에 보존제가 포함되지 않았으며, -20°C 이하에서 보관합니다.
- 카탈로그번호
- 5979-MSM6-P1ABX
- 판매단위
- pk
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Applications
ELISA (ELISA)
- Assay-dependent
Peptide Array (Array)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RET, 2976 |
| Immunogen | Recombinant fragment (around aa 702-848) of human RET protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is tested in direct ELISA.
- This antibody has only been tested in direct ELISA.
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with disorders such as:
- Multiple endocrine neoplasia type IIA and IIB
- Hirschsprung disease
- Medullary thyroid carcinoma
Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described but their biological validity has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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