Thermo Fisher Scientific Cyclin B1/CCNB1 Polyclonal Antibody
Cyclin B1/CCNB1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간 및 영장류 시료에서 반응성이 확인됨. Western blot과 Immunoprecipitation에 적합하며, 세포주기 G2/M 전이 연구에 활용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cyclin B1/CCNB1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human G2/mitotic-specific cyclin-B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
Cyclins bind to and regulate the activity of Cyclin-dependent protein kinases (CDKs).
Cyclin B1 (CCNB1) is a regulatory protein involved in mitosis and is essential for controlling the cell cycle at the G2/M transition.
Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF).
Two alternative transcripts exist: one constitutively expressed and one cell cycle–regulated, predominantly during G2/M phase.
Cyclin B1 accumulates during G2 phase and is degraded at the end of mitosis via APC-dependent destruction, which is required for cell cycle progression.
Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.