Thermo Fisher Scientific SOX2 Polyclonal Antibody
SOX2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 후 사용. 줄기세포 유지 및 발생 관련 연구에 적합.
- 카탈로그번호
- OSS00322W-150UL
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 250–318 of mouse SOX2 conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C for short term. For long term storage, store at −20 °C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: SOX2.
Target Information
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and cell fate determination.
The SOX2 protein is essential for stem-cell maintenance in the central nervous system and regulates gene expression in the stomach.
It lies within an intron of another gene, SOX2 overlapping transcript (SOX2OT). SOX2 may act as a transcriptional activator after forming a protein complex with other proteins.
Mutations in SOX2 have been associated with bilateral anophthalmia, optic nerve hypoplasia, and syndromic microphthalmia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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