Thermo Fisher Scientific SLC25A5/SLC25A6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2,000

-

Immunohistochemistry (IHC)

1:200-1:2,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from aa region 30-100 of human SLC25A6 conjugated to an immunogenic carrier protein was used as the antigen if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC25A5/SLC25A6,uniProtId:P12236-1,ncbiNodeId:9606,antigenRange:30-100,antigenLength:298,antigenImageFileName:OSS00325W-100UL_SLC25A5SLC25A6_P12236-1_Rabbit.svg,antigenImageFileNamePDP:OSS00325W-100UL_SLC25A5SLC25A6_P12236-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: SLC25A6, 5.

Target Information

SLC25A5 and SLC25A6 are members of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this genes functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. SLC25A5 forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of SLC25A5 gene has been shown to induce apoptosis and inhibit tumor growth. SLC25A6 is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.