Thermo Fisher Scientific LRWD1 Polyclonal Antibody
LRWD1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 인간과 생쥐 반응성, 항원 친화 크로마토그래피로 정제. 4°C에서 보관하며 연구용으로만 사용.
- 카탈로그번호
- A301868A
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- pk
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Thermo Fisher Scientific LRWD1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 432 and 482 of human leucine-rich repeats and WD repeat domain containing 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells.
Binds a combination of DNA and histone methylation repressive marks on heterochromatin.
Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3, and H4K20me3 in a cooperative manner with DNA methylation.
Required for silencing of major satellite repeats and may be important for ORC2, ORC3, and ORC4 stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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