Thermo Fisher Scientific LRWD1 Polyclonal Antibody
LRWD1 단백질을 타깃으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. 액상 형태로 제공되며 4°C에서 보관. 세포 주기 G1/S 전환 및 ORC 복합체 안정화 연구에 적합.
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Thermo Fisher Scientific LRWD1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 432 and 482 of human leucine-rich repeats and WD repeat domain containing 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells.
Binds a combination of DNA and histone methylation repressive marks on heterochromatin.
Associates with histone H3 and H4 trimethylation marks (H3K9me3, H3K27me3, H4K20me3) cooperatively with DNA methylation.
Required for silencing of major satellite repeats. May be important for ORC2, ORC3, and ORC4 stability.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 정보: A301-868A-M_LRWD1_Q9UFC0-1_Rabbit.svg, A301-868A-M_LRWD1_Q9UFC0-1_Rabbit_PDP.jpeg)
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