Thermo Fisher Scientific LRWD1 Polyclonal Antibody
LRWD1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 4°C에서 보관. 인간 단백질에 반응하며 연구용으로 적합.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and 250 of human leucine-rich repeats and WD repeat domain containing 1 (LRWD1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish the pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells.
Binds DNA and histone methylation repressive marks on heterochromatin, including histone H3 and H4 trimethylation marks (H3K9me3, H3K27me3, H4K20me3) in cooperation with DNA methylation.
Required for silencing of major satellite repeats and may be important for ORC2, ORC3, and ORC4 stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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