
Thermo Fisher Scientific NPC1L1 Polyclonal Antibody
Rabbit polyclonal antibody against human NPC1L1, suitable for WB and ICC/IF. Detects endogenous NPC1L1 involved in intestinal cholesterol absorption. Supplied as liquid, 1 mg/mL, affinity purified, stored at -20°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NPC1L1 (Accession Q9UHC9), corresponding to amino acid residues G186–L236 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852471 |
Product Specific Information
Antibody detects endogenous levels of total NPC1L1.
Target Information
Dietary consumption and intestinal cholesterol absorption contribute to plasma cholesterol levels, influencing the risk of coronary heart disease.
Niemann-Pick type C1 Like 1 protein (NPC1L1 or NPC3) is enriched in the small intestine and located in the brush border membrane of enterocytes, playing a critical role in intestinal cholesterol absorption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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