Thermo Fisher Scientific GnRHR Polyclonal Antibody
GnRHR 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 인간 시료 반응성. 고순도 Affinity chromatography 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GNRHR (Accession P30968), corresponding to amino acid residues T42–L92 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852464 |
Product Specific Information
This antibody detects endogenous levels of total GNRHR.
Target Information
This gene encodes the receptor for type 1 gonadotropin-releasing hormone (GnRH). It belongs to the seven-transmembrane, G-protein coupled receptor (GPCR) family. The receptor is expressed on pituitary gonadotrope cells, lymphocytes, breast, ovary, and prostate. Upon GnRH binding, it activates a phosphatidylinositol-calcium second messenger system, leading to the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). Mutations in this gene may cause hypogonadotropic hypogonadism (HH). Multiple transcript variants and isoforms are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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