Thermo Fisher Scientific eIF2b gamma Monoclonal Antibody (1H3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:200

-

Immunocytochemistry (ICC/IF)

1:10-1:100

-

Immunoprecipitation (IP)

3 µg

-

RNA Immunoprecipitation (RIP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Non-human primate, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1H3

Immunogen

Full length human eIF2B3 produced in HEK293T cells. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:eIF2b gamma,uniProtId:Q9NR50-1,ncbiNodeId:9606,antigenRange:1-452,antigenLength:452,antigenImageFileName:MA1-078_eIF2b_gamma_Q9NR50-1_House_mouse.svg,antigenImageFileNamePDP:MA1-078_eIF2b_gamma_Q9NR50-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1mg/mL BSA, 30% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2536735

Product Specific Information

MA1-078 detects eIF2B3 in human, non-human primate and rat samples and has been successfully used in Western blot, ICC/IF, IHC (P) and immunoprecipitation applications.

The immunogen for MA1-078 is full length human eIF2B3 produced in HEK293T cells.

Target Information

EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.