Thermo Fisher Scientific Hepatitis C Virus Core Antigen Monoclonal Antibody (C7-50)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

MA1-080 detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
It has been successfully used in Western blot, immunoprecipitation, immunofluorescence, and ELISA procedures.
In Western blot, this antibody detects a single ~21 kDa protein representing the HCV core protein in various transfected cell lines.
Immunofluorescence staining of HCV core protein in transfected chimp hepatocytes shows a cytoplasmic and vesicular staining pattern.

The MA1-080 immunogen is purified HCV core-GST fusion protein (genotype 1b).
This antibody recognizes an epitope between amino acid residues 21–40 of the HCV core protein, a sequence conserved among different HCV strains.

Target Information

Hepatitis C Virus (HCV) is a positive-sense, single-stranded RNA virus belonging to the Flaviviridae family.
Its genome (~10,000 nucleotides) encodes a single polyprotein (~3,000 amino acids), which is processed into structural and non-structural proteins required for viral replication.
Multiple genotypes of HCV exist, differing slightly in genomic sequence and treatment response to interferon alpha.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.