Thermo Fisher Scientific SARS-CoV-2 ORF9b Polyclonal Antibody
SARS-CoV-2 ORF9b 단백질을 인식하는 토끼 유래 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 높은 순도의 액상 형태이며, PBS 버퍼와 글리세롤 포함. 바이러스 단백질 연구 및 면역반응 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–97 of coronavirus ORF9b (P0DTD2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.55 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901581 |
Product Specific Information
- Positive Samples: 293T
- Immunogen Sequence:
MDPKISEMHP ALRLVDPQIQ LAVTRMENAV GRDQNNVGPK VYPIILRLGS PLSLNMARKT LNSLEDKAFQ LTPIAVQMTK LATTEELPDE FVVVTVK
Target Information
ORF9b plays a role in the inhibition of host innate immune response by targeting the mitochondrial-associated adapter MAVS. Mechanistically, it usurps the E3 ligase ITCH to trigger the degradation of MAVS, TRAF3, and TRAF6. In addition, ORF9b causes mitochondrial elongation by triggering ubiquitination and proteasomal degradation of dynamin-like protein 1 (DNM1L).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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