Thermo Fisher Scientific Phospho-RPS6 (Ser240, Ser244) Polyclonal Antibody
Phospho-RPS6 (Ser240, Ser244) 폴리클로날 항체로 인간, 생쥐, 랫트 반응성. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용 가능. Protein A로 정제된 액상 형태, 1 mg/mL 농도. 세포 성장 및 단백질 합성 조절 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human S6 Ribosomal Protein around the phosphorylation site of Ser240/244 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ribosomes are organelles that catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit. These subunits contain four RNA species and approximately 80 distinct proteins. The RPS6 gene encodes a cytoplasmic ribosomal protein that is part of the 40S subunit and belongs to the S6E family. It serves as a major substrate for protein kinases in the ribosome, with phosphorylation occurring at five C-terminal serine residues. Phosphorylation is triggered by various stimuli, including growth factors and mitogens, while dephosphorylation occurs during growth arrest. This protein is implicated in the regulation of cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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