
Thermo Fisher Scientific PRRX1 Monoclonal Antibody (OTI1C4), TrueMAB
PRRX1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 무보존제, 동결건조 형태이며 재구성 후 1 mg/mL 농도로 사용 가능합니다. 인간 PRRX1 전체 길이 재조합 단백질을 면역원으로 제작되었습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C4 |
| Immunogen | Full length human recombinant protein of human PRRX1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The homeobox DNA-binding domain is a conserved 60 amino acid motif found across species and functions in DNA binding via a helix-turn-helix structure.
PRRX1 (paired related homeobox 1), also known as PMX1 or PHOX1, is a 245 amino acid nuclear protein containing one OAR domain and one homeobox DNA-binding domain, belonging to the paired homeobox family.
It acts as a transcriptional co-activator enhancing SRF-dependent gene expression and regulates creatine kinase-M transcriptional activity, contributing to mesodermal muscle type formation.
PRRX1 exists as two alternatively spliced isoforms, PMX1-A and PMX1-B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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