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Thermo Fisher Scientific Prohibitin Monoclonal Antibody (PHB, 3193)
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Thermo Fisher Scientific Prohibitin Monoclonal Antibody (PHB, 3193)

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인간 Prohibitin 단백질을 인식하는 Mouse 모노클로날 항체로, WB 및 IHC(P) 등 다양한 응용에 적합. Recombinant PHB 단백질을 면역원으로 사용하며, Protein A/G로 정제된 액상 형태. 세포 증식 억제 및 종양 억제 연구에 활용 가능.

카탈로그번호
5245-MSM3-P1
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오후 01:18
Thermo Fisher Scientific 5245-MSM3-P1 Prohibitin Monoclonal Antibody (PHB, 3193) 100 ug pk판매 단위 pk ·
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825,100원VAT 포함 907,610원

Thermo Fisher Scientific · Thermo Fisher Scientific Prohibitin Monoclonal Antibody (PHB, 3193)

Applications

Application Tested Dilution Notes
Western Blot (WB) 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) 1–2 µg/mL
Peptide Array (Array) Assay-dependent

Product Specifications

Property Description
Species Reactivity Human
Host / Isotype Mouse / IgG2b, kappa
Class Monoclonal
Type Antibody
Clone PHB, 3193
Immunogen Recombinant human PHB protein fragment (aa167–261)
Conjugate Unconjugated
Form Liquid
Concentration 200 µg/mL
Purification Protein A/G
Storage Buffer PBS, pH 7.4, with 0.05% BSA
Contains 0.05% sodium azide
Storage Conditions 4°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
  • Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

Prohibitin is encoded by an evolutionarily conserved gene expressed ubiquitously. It functions as a negative regulator of cell proliferation and may act as a tumor suppressor. Mutations in PHB have been associated with sporadic breast cancer. Two transcripts with varying 3' untranslated regions are expressed; the longer transcript is more abundant in proliferating tissues, suggesting a regulatory role as a trans-acting RNA.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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