Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (r2H11)
인체, 마우스, 랫트 반응성을 가진 단클론 항-티로글로불린 항체로, 갑상선 세포 마커 분석에 적합합니다. 파라핀 및 PFA 고정 조직 면역조직화학(IHC)에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | r2H11 |
| Immunogen | Human thyroid follicular cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells.
It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Thyroid disorders are often autoimmune in origin, and anti-thyroglobulin autoantibodies were the first such factor to be discovered.
Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis.
It is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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