Thermo Fisher Scientific Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (r2H11)
Thyroglobulin 단백질을 표적하는 마우스 단클론 항체로, IHC(P) 및 IHC(PFA) 실험에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, Protein A/G로 정제된 액상 형태입니다. 갑상선 관련 질환 연구 및 표지용으로 활용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | r2H11 |
| Immunogen | Human thyroid follicular cells (Thyroglobulin, UniProt ID: P01266-1, antigen range: 1–2768) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3. Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first such factor to be discovered. Anti-hTG is present in autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves disease, with the highest levels in Hashimoto thyroiditis. It is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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