Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI3C5), TrueMAB
인간 CD4 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 유세포분석에 사용 가능. 고순도의 액상 형태로 제공되며, PBS/BSA/glycerol buffer에 보존. 연구용으로 HIV 및 면역 관련 연구에 적합.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000 | |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C5 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells) but may also be expressed by monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, spleen, and specific regions of the brain, gut, and other non-lymphoid tissues.
CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also serve as a mediator of neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Multiple alternatively spliced transcripts have been identified in this gene (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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