Thermo Fisher Scientific PGP9.5 Polyclonal Antibody
Rabbit polyclonal antibody against PGP9.5 (UCH-L1) for WB and IHC applications. Useful neuronal marker for neurodegenerative disease studies. Supplied as liquid, unconjugated form, stored at -20°C.
- 카탈로그번호
- RA12103-xxxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PGP9.5 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ASSEDTLLKDAAKVCR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
PGP9.5 (Protein Gene Product 9.5, UCH-L1, PARK5) is a neuron-specific protein, structurally and immunologically distinct from neuron-specific enolase. It has a molecular weight of 27 kDa and belongs to the ubiquitin carboxyl-terminal hydrolase family 1 (peptidase family C12). PGP9.5 possesses ubiquitin hydrolase and ligase activities, hydrolyzing small C-terminal adducts of ubiquitin to generate ubiquitin monomers.
PGP9.5 is expressed in neurons and nerve fibers throughout the central and peripheral nervous system, in neuroendocrine cells, renal tubule segments, spermatogonia, Leydig cells of the testis, ova, and corpus luteum cells. Overexpression is associated with non-small cell lung cancer, while decreased expression is linked to Huntington and Alzheimer diseases. Due to its presence in neuronal inclusions, PGP9.5 serves as a useful neuronal marker and is valuable for studies of neurodegenerative disorders such as Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.