Thermo Fisher Scientific CD1b Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human CD1B (NP_0017551) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD1b,uniProtId:P29016-1,ncbiNodeId:9606,antigenRange:18-303,antigenLength:333,antigenImageFileName:PA5-93051_CD1b_P29016-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93051_CD1b_P29016-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806604

Product Specific Information

Immunogen sequence: SEHAFQGPTS FHVIQTSSFT NSTWAQTQGS GWLDDLQIHG WDSDSGTAIF LKPWSKGNFS DKEVAELEEI FRVYIFGFAR EVQDFAGDFQ MKYPFEIQGI AGCELHSGGA IVSFLRGALG GLDFLSVKNA SCVPSPEGGS RAQKFCALII QYQGIMETVR ILLYETCPRY LLGVLNAGKA DLQRQVKPEA WLSSGPSPGP GRLQLVCHVS GFYPKPVWVM WMRGEQEQQG TQLGDILPNA NWTWYLRATL DVADGEAAGL SCRVKHSSLE GQDIILYWRN PTSIGS; Positive Samples: NCI-H125; Cellular Location: Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein

Target Information

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.