Thermo Fisher Scientific CD1b Polyclonal Antibody
Thermo Fisher Scientific의 CD1b Polyclonal Antibody는 인간 CD1b 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/glycerol 저장용액, 세포막 단백질 검출에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 18–303 of human CD1B (NP_0017551) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.13 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806604 |
Product Specific Information
Immunogen sequence:
SEHAFQGPTS FHVIQTSSFT NSTWAQTQGS GWLDDLQIHG WDSDSGTAIF LKPWSKGNFS DKEVAELEEI FRVYIFGFAR EVQDFAGDFQ MKYPFEIQGI AGCELHSGGA IVSFLRGALG GLDFLSVKNA SCVPSPEGGS RAQKFCALII QYQGIMETVR ILLYETCPRY LLGVLNAGKA DLQRQVKPEA WLSSGPSPGP GRLQLVCHVS GFYPKPVWVM WMRGEQEQQG TQLGDILPNA NWTWYLRATL DVADGEAAGL SCRVKHSSLE GQDIILYWRN PTSIGSPositive Samples: NCI-H125
Cellular Location: Cell membrane, Endosome membrane, Lysosome membrane, Single-pass type I membrane protein
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to MHC proteins and forming heterodimers with beta-2-microglobulin. CD1 proteins present lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. CD1 family members differ in cellular localization and lipid ligand specificity. The encoded protein localizes to late endosomes and lysosomes via a tyrosine-based motif and requires vesicular acidification to bind lipid antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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