Thermo Fisher Scientific CARS Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:10-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 469-748 of human CARS (NP_0017421) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CARS,uniProtId:P49589-1,ncbiNodeId:9606,antigenRange:469-748,antigenLength:748,antigenImageFileName:PA5-93043_CARS_P49589-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93043_CARS_P49589-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.49 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806599

Product Specific Information

Immunogen sequence: ILRAPVDITG QFEKWGEEEA ELNKNFYDKK TAIHKALCDN VDTRTVMEEM RALVSQCNLY MAARKAVRKR PNQALLENIA LYLTHMLKIF GAVEEDSSLG FPVGGPGTSL SLEATVMPYL QVLSEFREGV RKIAREQKVP EILQLSDALR DNILPELGVR FEDHEGLPTV VKLVDRNTLL KEREEKRRVE EEKRKKKEEA ARRKQEQEAA KLAKMKIPPS EMFLSETDKY SKFDENGLPT HDMEGKELSK GQAKKLKKLF EAQEKLYKEY LQMAQNGSFQ; Positive Samples: HeLa, MCF7, Mouse liver; Cellular Location: Cytoplasm

Target Information

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.