Thermo Fisher Scientific PGRMC2 Polyclonal Antibody
PGRMC2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. 인간 시료에 반응하며 ICC/IF 및 유세포분석(Flow Cytometry)에 적합. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS(pH 7.3) 버퍼에 0.5% BSA와 0.02% sodium azide를 포함. 연구용 전용 제품.
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- PA5142221
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DEEDTKDHNKQD (aa 212–223) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932875 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.
Target Information
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 or PMBP, is a single-pass membrane protein belonging to the cytochrome b5 family (MAPR subfamily). Expressed in sperm, PGRMC2 functions as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. It shares approximately 50% sequence identity with PGRMC1. Loss of PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, suggesting a potential role in metastasis suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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