Thermo Fisher Scientific CDKN2AIP Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MAQEVSEYLS QNPRVAAWVE ALRCDGETDK HWRHRRDFLL RNAGDLAPAG GAASASTDEA ADAESGTRNR QLQQLISFSM AWANHVFLGC RYPQKVMDKI LSMAEGIKVT DAPTYTTRDE LVAKVKKRGI SSSNEGVEEP SKKRVIEGKN SSAVEQDHAK TSAKTERASA QQENSSTCIG SAIKSESGNS ARSSGISSQN SSTSDGDRSV SSQSSSSVSS QVTTAGSGKA SEAEAPDKHG SSFVSLLKSS VNSHMTQSTD SRQQSGSPKK SALEGSSASA SQSSSEIEVP LLGSSGSSEV ELPLLSSKPS SETASSGLTS KTSSEASVSS SVAKNSSSSG TSLLTPKSSS STNTSLLTSK STSQVAASLL ASKSSSQTSG SLVSKSTSLA SVSQLASKSS SQTSTSQLPS KSTSQSSESS VKFSCKLTNE DVKQKQPFFN RLYKTVAWKL VAVGGFSPNV NHGELLNAAI EALKATLDVF FVPLKELADL PQNKSSQESI VCELRCKSVY LGTGCGKSKE NAKAVASREA LKLFLKKKVV VKICKRKYRG SEIEDLVLLD EESRPVNLPP ALKHPQELL

Target Information

CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.