Thermo Fisher Scientific BMP2K Monoclonal Antibody (4B19)
BMP2K 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(4B19). Western blot 및 ELISA에 적합하며, 인간 단백질에 반응. 비결합형 액상 포맷으로, 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B19 |
| Immunogen | BMP2K (AAH36021, 540 a.a. ~ 650 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
YQQAFFQQQM LAQHQPSQQQ ASPEYLTSPQ EFSPALVSYT SSLPAQVGTI MDSSYSANRS VADKEAIANF TNQKNISNPP DMSGWNPFGE DNFSKLTEEE LLDREFDLLR S
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis, and apoptosis.
BMP2K (BMP2 inducible kinase), also known as BIKE, is a 1,161 amino acid nuclear protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. It is thought to be involved in osteoblast differentiation and catalyzes the ATP-dependent phosphorylation of bone morphogenic proteins (BMPs), which are essential for proper cartilage and bone formation. Through its catalytic activity, BMP2K may play a role in signaling pathways that mediate bone growth and cellular differentiation. Three isoforms of BMP2K exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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