Thermo Fisher Scientific Mucolipin 3 Polyclonal Antibody
Rabbit polyclonal antibody against human Mucolipin 3. Validated for WB and IHC applications. Lyophilized and unconjugated form. Suitable for research use in studying hearing loss and related cellular mechanisms.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:3,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:3,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Mucolipin 3 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Mucolipin 3.
Target Information
Mucolipin 3 is expressed in the cochlea, particularly in the inner and outer hair cells.
Defects in Mcoln3 cause the varitin-waddler (Va) phenotype, characterized by early-onset hearing loss, vestibular defects, pigmentation abnormalities, and perinatal lethality.
The varitin-waddler Jackcon (Va-J) phenotype is similar but less severe.
Belongs to the transient receptor family, polycystin subfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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