Thermo Fisher Scientific Mucolipin 1 Polyclonal Antibody
Human Mucolipin 1 단백질을 인식하는 sheep polyclonal antibody. Western blot 및 IHC에 적합하며, 동결건조 형태로 제공. 4°C 단기 보관, 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Mucolipin 1 (isoform 1) conjugated to immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Mucolipin 1, isoform 1.
Target Information
Defects in Mucolipin-1 cause mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities such as corneal opacity, retinal degeneration, and strabismus. Storage bodies of lipids and water-soluble substances are observed in nearly all cell types of affected patients. Most patients cannot speak or walk independently and reach a developmental level of 1–2 years. All patients exhibit constitutive achlorhydria with secondary elevation of serum gastrin levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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