Thermo Fisher Scientific TRPV2 Polyclonal Antibody
TRPV2 단백질을 인식하는 sheep 유래 polyclonal 항체로, Western blot 및 IHC에 사용 가능. 합성 human TRPV2 펩타이드를 면역원으로 제작. 비결합형, 동결건조 형태로 제공되며 연구용으로만 사용.
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Thermo Fisher Scientific TRPV2 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:300–1:2,000
- Immunohistochemistry (IHC): 1:300–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPV2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2303876 |
Product Specific Information
Reconstitute with 100 µL of distilled water before use.
Target Information
VLR-1 (also known as TRPV2) is a calcium-permeable, non-selective cation channel exhibiting outward rectification. It is regulated by growth factors such as IGF1, PDGF, and morphogenetic neuropeptides.
TRPV2 is activated by high temperatures (threshold ≈ 52°C) rather than capsaicin, acid, or moderate heat. Within sensory ganglia, TRPV2 is expressed in medium- to large-diameter neurons, suggesting a role in high-threshold heat response.
Expression is not limited to the sensory nervous system, implying activation by stimuli other than heat. TRPV2 is one of six members of the vanilloid-like TRP-channel family, now classified as the TRPV family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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