Thermo Fisher Scientific Phospho-ERK1/ERK2 (Thr202, Tyr204) Recombinant Rabbit Monoclonal Antibody (ERK12T202Y204-A11), APC
ERK1/ERK2 Thr202/Tyr204 인산화 부위를 특이적으로 인식하는 APC 결합 재조합 토끼 단클론 항체. Flow Cytometry에 적합하며, 인간 및 마우스 시료에 반응. 높은 특이성과 재현성을 제공하며, 단백질 인산화 신호 연구에 적합.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ERK12T202Y204-A11 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr202/Tyr204 of human phospho Erk1/2 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896833 |
Available Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and expressed, and individual clones are screened to select optimal candidates.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
ERK1 and ERK2 are key kinases involved in regulating meiosis, mitosis, and postmitotic cellular functions. They are activated by various stimuli such as growth factors, cytokines, viral infections, and GPCR ligands.
Upon activation, ERKs phosphorylate cytoplasmic targets or translocate to the nucleus to activate transcription factors including c-Fos and Elk-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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