Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody
TRAF3IP1 단백질 검출용 Thermo Fisher Scientific의 고품질 Rabbit Polyclonal 항체입니다. Western blot에 최적화되어 있으며 Human, Mouse, Rat 시료에 반응합니다. SDS-PAGE 기준 95% 이상 순도, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA575785
- 판매단위
- pk
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Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human TRAF3IP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719513 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation, and apoptosis in various cell types. TNFR-associated factors (TRAFs) are a family of proteins initially discovered as downstream signal transducers of the TNFR superfamily.
TRAF3 contains an N-terminal ring finger/zinc finger region essential for downstream signaling. MIP-T3 is associated with TRAF3, binding to taxol-stabilized microtubules and tubulin in vitro, and recruits TRAF3 to microtubules when both proteins are overexpressed.
The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3 and may provide a novel mechanism for sequestering TRAF3 to the cytoskeletal network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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