Thermo Fisher Scientific TNFRSF11B Monoclonal Antibody (9C1)
TNFRSF11B 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC/IF에 사용 가능. Osteoprotegerin 관련 연구에 적합하며, 고순도 Protein G 정제 및 안정한 PBS/glycerol 버퍼 제공. 연구용으로만 사용.
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Thermo Fisher Scientific TNFRSF11B Monoclonal Antibody (9C1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9C1 |
| Immunogen | Recombinant protein within Human Osteoprotegerin (aa 1–401) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848828 |
Product Specific Information
Positive Control: K562, MCF-7, rat lung tissue, human liver tissue, human small intestine tissue, mouse heart tissue.
Target Information
The TNFRSF11B gene encodes a member of the TNF-receptor superfamily. The protein acts as an osteoblast-secreted decoy receptor and negatively regulates bone resorption. It binds specifically to the osteoprotegerin ligand, both being key extracellular regulators of osteoclast development. Mouse studies suggest roles in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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