Thermo Fisher Scientific Oncostatin M Polyclonal Antibody
인간, 생쥐, 랫드에 반응하는 Oncostatin M 폴리클로날 항체로 Western blot, ICC/IF, ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며 PBS/glycerol 용액 형태로 제공됩니다. 세포 성장 및 분화 연구용으로 권장됩니다.
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Thermo Fisher Scientific Oncostatin M Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 26–252 of human Oncostatin M (NP_065391.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.19 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914546 |
Product Specific Information
- Positive test controls: HepG2, NIH/3T3, Mouse uterus, Mouse heart
- Target localization: Secreted
Immunogen sequence:
AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRRT RPSRKGKRLM TRGQLPR
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in neurogenesis, osteogenesis, and hematopoiesis. Produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It promotes fibroblast, smooth muscle, and Kaposi’s sarcoma cell proliferation, but inhibits growth of certain normal and tumor cell lines. OSM also induces cytokine release (IL-6, GM-CSF, G-CSF) from endothelial cells and enhances LDL receptor expression in hepatoma cells. Structurally and functionally related to LIF, IL-6, and CNTF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-120974_Oncostatin_M_P13725-1_Rabbit.svg, PA5-120974_Oncostatin_M_P13725-1_Rabbit_PDP.jpeg)
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