Thermo Fisher Scientific STEAP4 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Antibody. Western Blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.02% sodium azide 포함. 2–8°C 보관, 장기 보관 시 -20°C 권장. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
- Suggested Positive Control: Rat liver tissue lysate
- Blocking Peptide: PEP-0524
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide from near the center of human STEAP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157860 |
Target Information
The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to STEAP2 and STEAP3, STEAP4 promotes both iron and copper reduction. It is highly expressed in placenta, lung, heart, and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting a potential role in cell proliferation and prostate cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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