Thermo Fisher Scientific claudin 14 Polyclonal Antibody
Claudin 14 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합하며 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었고, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Claudin 14 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 177–239 of Claudin 14 (Uniprot ID: O95500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153197 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa, HepG2
- Predicted reactivity: Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tight junctions are one mode of cell-to-cell adhesion in epithelial or endothelial sheets, forming continuous seals around cells to serve as a physical barrier preventing solute and water passage through the paracellular space. Claudin family proteins are integral membrane components of these junctions. Claudin 14 binds specifically to the WW domain of Yes-associated protein. Mutations in this gene can cause autosomal recessive nonsyndromic sensorineural deafness. Multiple transcript variants encoding the same protein have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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