Thermo Fisher Scientific EBP50 Polyclonal Antibody
EBP50/NHERF1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot, IHC, IP에 적합합니다. 높은 특이성과 재현성을 제공하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific EBP50 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human SLC9A3R1 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902864 |
Target Information
NHERF1 (Na⁺/H⁺ exchanger regulatory factor 1), also known as EBP50 (ezrin, radixin, moesin-binding phosphoprotein 50), is an adaptor protein that associates with beta-catenin and is required for its localization at cell-cell junctions. It interacts with various G protein-coupled receptors and regulates their trafficking, as well as sodium-hydrogen exchange and sodium-dependent phosphate transport.
NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains a C-terminal ERM (ezrin, radixin, moesin)-binding region and two N-terminal PDZ domains, enabling intramolecular conformation that regulates its interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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