Thermo Fisher Scientific Phospho-MAP2K4 (Thr261) Polyclonal Antibody
MAP2K4 단백질의 Thr261 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot과 ELISA에 최적화되어 있으며, Human, Mouse, Rat 시료에 반응. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 연구용에 적합.
- 카탈로그번호
- PA5117175
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Phospho-MAP2K4 (Thr261) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around T261 of human MAP2K4 (NP_0030011) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901805 |
Product Specific Information
- Positive Samples: C6
- Immunogen Sequence: AKTRD
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase belonging to the STE7 family. It phosphorylates and activates JNK1/2 and p38 MAP kinases, preferentially targeting tyrosine residues of JNKs. MAP2K4 plays a key role in cellular stress responses and inflammatory signaling. It is implicated in carcinogenesis, with loss-of-function mutations observed in lung and pancreatic tumors, while also exhibiting pro-oncogenic roles in certain contexts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-117175_MAP2K4_P45985-1_Rabbit.svg, PA5-117175_MAP2K4_P45985-1_Rabbit_PDP.jpeg)
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