Thermo Fisher Scientific CLIC5 Monoclonal Antibody (CLIC5-02)
CLIC5 단백질을 인식하는 Mouse monoclonal 항체로, Western blot 및 Flow cytometry에 적합합니다. Human 시료에 반응하며, 단백질 A로 정제된 액상형 제품입니다. 4°C에서 보관하며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA528624
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CLIC5-02 |
| Immunogen | Human CLIC5a (amino acids 160–173) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745583 |
Additional Formats
Product Specific Information
This antibody recognizes CLIC5a, a 32 kDa intracellular protein associated with actin complexes. Cross-reactivity with CLIC5b has not been determined.
Target Information
CLIC5 encodes a protein required for normal hearing and the formation of stereocilia in the inner ear. It can insert into membranes to form ion channels that may transport chloride ions.
CLIC5 plays a role in transepithelial ion absorption, secretion, and maintenance of glomerular endothelial and podocyte architecture.
It belongs to the chloride intracellular channel (CLIC) family and associates with actin-based cytoskeletal structures.
Alternative splicing results in multiple isoforms.
Diseases associated with CLIC5 include Deafness, Autosomal Recessive 103 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type DFNB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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